Who won in NFL on September 22, 2025?

1 NFL game went final on September 22, 2025. Winners: Chiefs.

What was the highest-scoring NFL game on September 22, 2025?

Chiefs at Giants was the highest-scoring, combining for 31 points (Chiefs 22, Giants 9).

Home › NFL › Recaps › September 22, 2025

NFL Scores & Recap — September 22, 2025

All 1 NFL final from September 22, 2025, with box-score recaps and standout performers below — plus our model scoreboard: what Signal Labs projected before first pitch versus what actually happened.

🎯 Our model scoreboard

Every NFL game · September 22, 2025

Chiefs @ Giants

22–9

Chiefs beat Giants 22–9. The teams combined for 31 points.

NFL model board

See every pick before the first pitch

Signal Labs logs every model pick to a public ledger — wins and losses. See the full track record → · Pricing →

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